Substance	Sorafenib
Brand name:	Nexavar
Description
	Chemotherapy
	Most often, the drug is prescribed to patients diagnosed with metastatic renal cell carcinoma
Brands:	Nexavar
Availability:	Prescription needed
Pregnancy:	Consult a doctor
Alcohol:	Not detected with light alcohol consumption
Side Effects:	Hearing Loss, Increased Menstrual Flow Or Vaginal Bleeding, Increased Thirst
Interactions:	Fluoxetine, Levothyroxine, Ondansetron
For informational purposes only. Consult your local medical authority for advice.

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What may interact with Nexavar?

Tell your doctor about all other cancer medicines you use, especially cisplatin, cyclophosphamide, docetaxel, doxorubicin, fluorouracil, gemcitabine, irinotecan, paclitaxel, or tamoxifen.

Many drugs can interact with sorafenib. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with sorafenib, especially:

• dexamethasone;

• neomycin;

• St. John's wort;

• a blood thinner (warfarin, Coumadin);

• seizure medication--carbamazepine, fosphenytoin, phenobarbital, phenytoin; or

• tuberculosis medicine--rifabutin, rifampin.

This list is not complete and many other drugs can interact with sorafenib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

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